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Autozygosity Mapping

Draft Paper and 4 Excel spreadsheets (7MB zip files) CG Woods et al J Med Genet 2004 41:e101

These files relate to the use of the 2nd version of the Affymetrix 10K SNP chip for identifying regions of homozygosity.

These versions of ExcludeAR work with the latest 11K Affymetirx SNP chip (which has slightly fewer, but more useable, SNPs than the first chip).

There is still a gross deficiency of subtelomeric SNPs, so if you donąt find linkage check these regions.

The "lite" versions of ExcludeAR for the 2nd Affymetrix SNP chip needed expanding as follows before adding your data,

This may take a while for Excel to recalculate!

ExcludeAR1liteCHIP2   -  Copy cells Q19-DC19 and Paste them into Q11163 ­ DC11163

ExcludeAR2liteCHIP2   -  Copy cells Q19-DC19 and Paste them into Q11163 ­ DC11163

ExcludeAR3liteCHIP2   -  Copy cells R19-DL19 and Paste them into R11163 ­ DN11163

ExcludeAR4liteCHIP2   -  Copy cells S19-CO19 and Paste them into S11163 ­ CO11163 

We apologise for this but the original spreadsheets are large and the Zipped files are executables; this lead to downloading problems.

 

User Guide Editor: Dr Ruth Charlton PhD DipRCPath. Copyright © 2007 . Yorkshire Regional DNA Laboratory. All rights reserved.